E-ISSN 2347-6923 | ISSN 2277-4092
 
2026, Vol: 15, Issue: 3
15 / 3Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles

Original Research 


Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management

Ravi Pratap Singh, Govind Sahaya Shukla, Manisha Goyal, Rajaram Agarwal, Pradeep Kumar Prajapati.


Abstract
Vatashleshmik Jwarghna Granules (VJGr), a proprietary polyherbal ayurvedic formulation has been used clinically to treat influenza . VJGr comprises granules of 12 herbs Vasa (Adhatoda vasica ), Kantkari (Solanum surattense), Haridra (Curcuma longa), Guduchi (Tinospora cordifolia), Sunthi (Zingiber officinale), Bharangi (Clerodendrum serratum), Talish Patra (Abies webbiana), Bhumyamalaki (Phyllanthus urinaria), Madhuyashthi (Glycyrrhiza glabra), Tulsi Patra (Ocimum sanctum), Marich (Piper nigrum), and Lavang (Syzygium aromaticum). The present study evaluated the sub-acute toxicity study along with the limit test of VJGr in the Wistar rat’s experimental model as per the guidelines of the Economic Co-operation and Development (OECD) 407. A Subacute Toxicity study was conducted in three groups (Control, two testing groups with two dose levels of 500 and 1000 mg/kg body weight once a day) for 28 days. There were no alterations in the general behavioral parameters. Clinical chemistry values and hematological parameters were found to be significantly similar in comparison to the control group after the completion of the study. Moreover, the vital organs (heart, kidney, liver) also showed no histopathological evidence of pathological lesions. The study found that VJGr exhibited no toxic effects and may be effectively used to treat influenza

Key words: Vatashleshmik Jwaraghna Granules, HPTLC, Ayurvedic granules, Safety study, OECD 407


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ravi Pratap Singh
Articles by Govind Sahaya Shukla
Articles by Manisha Goyal
Articles by Rajaram Agarwal
Articles by Pradeep Kumar Prajapati
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Singh RP, Shukla GS, Goyal M, Agarwal R, Prajapati PK. Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management. AAM. 2026; 15(3): 586-601. doi:10.5455/AAM.189038

Web Style

Singh RP, Shukla GS, Goyal M, Agarwal R, Prajapati PK. Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management. https://www.aamjournal.in/?mno=189038 [Access: June 29, 2026]. doi:10.5455/AAM.189038

AMA (American Medical Association) Style

Singh RP, Shukla GS, Goyal M, Agarwal R, Prajapati PK. Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management. AAM. 2026; 15(3): 586-601. doi:10.5455/AAM.189038


Vancouver/ICMJE Style

Singh RP, Shukla GS, Goyal M, Agarwal R, Prajapati PK. Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management. AAM. (2026), [cited June 29, 2026]; 15(3): 586-601. doi:10.5455/AAM.189038


Harvard Style

Singh, R. P., Shukla, . G. S., Goyal, . M., Agarwal, . R. & Prajapati, . P. K. (2026) Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management. AAM, 15 (3), 586-601. doi:10.5455/AAM.189038


Turabian Style

Singh, Ravi Pratap, Govind Sahaya Shukla, Manisha Goyal, Rajaram Agarwal, and Pradeep Kumar Prajapati. 2026. Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management. Annals of Ayurvedic Medicine, 15 (3), 586-601. doi:10.5455/AAM.189038


Chicago Style

Singh, Ravi Pratap, Govind Sahaya Shukla, Manisha Goyal, Rajaram Agarwal, and Pradeep Kumar Prajapati. "Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management." Annals of Ayurvedic Medicine 15 (2026), 586-601. doi:10.5455/AAM.189038


MLA (The Modern Language Association) Style

Singh, Ravi Pratap, Govind Sahaya Shukla, Manisha Goyal, Rajaram Agarwal, and Pradeep Kumar Prajapati. "Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management." Annals of Ayurvedic Medicine 15.3 (2026), 586-601. Print. doi:10.5455/AAM.189038


APA (American Psychological Association) Style

Singh, R. P., Shukla, . G. S., Goyal, . M., Agarwal, . R. & Prajapati, . P. K. (2026) Analytical Profiling and Sub-Acute Toxicity Study of an Ayurvedic Polyherbal Formulation for Influenza Management. Annals of Ayurvedic Medicine, 15 (3), 586-601. doi:10.5455/AAM.189038


Author LoginReviewer LoginAbout PublisherOpen Access PolicyEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyLicense InformationCopyright Information

About Annals of Ayurvedic Medicine

Annals of Ayurvedic Medicine (AAM) is the organ of ‘Association of Ayurvedic Physicians of India\'(AAPI), which is a national representative body of Ayu ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


Editorial Office :

Prof Sanjeev Rastogi

Vatsala Hospital, Tulsi Das Marg, Lucknow-226003, INDIA

Main Office :

6, Ganga Bag Colony, Lanka, Varanasi -221005, INDIA

Editorial Contact:
Email: info@sapi.org.in

Email: rastogisanjeev@rediffmail.com

Mobile: 0091-9415022955