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2026, Vol: 15, Issue: 3
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Review Article 


Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.

Sarika M Makwana, Dipali N Parekh, Prashant Bedarkar, Pro B J Patgiri.


Cited By:1

Abstract
Background: In Ayurvedic therapeutics, Manahshila (Realgar, As2S3) is widely utilized drug since the Samhita period. Only few researches however have been carried out on its safety and efficacy. Present work aims to review published case studies and clinical trials on formulations containing Manahshila and to see its safety and efficacy. Materials & Method: Published Case studies and Clinical trials on Manahshila (Realgar) and compound formulations containing it were reviewed through various search engines and database like Google, Google scholar, Yahoo, PubMed etc. Results: Total 15 published research articles were reviewed including four case studies, ten clinical trials on formulations containing Manahshila and one clinical trial on Ardraka shodhita Mananhshila.
Conclusion: reviewed researches on formulations containing Manahshila suggest that Manahshila and its containing formulations are safe and effective in different dosage form in treating different diseases conditions.

Key words: Ayurveda, Arsenicals, Efficacy, Manahshila, Safety


 
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How to Cite this Article
Pubmed Style

Makwana SM, Parekh DN, Bedarkar P, Patgiri PBJ. Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.. AAM. 2021; 10(2): 165-176. doi:10.5455/AAM.91471

Web Style

Makwana SM, Parekh DN, Bedarkar P, Patgiri PBJ. Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.. https://www.aamjournal.in/?mno=91471 [Access: June 27, 2026]. doi:10.5455/AAM.91471

AMA (American Medical Association) Style

Makwana SM, Parekh DN, Bedarkar P, Patgiri PBJ. Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.. AAM. 2021; 10(2): 165-176. doi:10.5455/AAM.91471


Vancouver/ICMJE Style

Makwana SM, Parekh DN, Bedarkar P, Patgiri PBJ. Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.. AAM. (2021), [cited June 27, 2026]; 10(2): 165-176. doi:10.5455/AAM.91471


Harvard Style

Makwana, S. M., Parekh, . D. N., Bedarkar, . P. & Patgiri, . P. B. J. (2021) Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.. AAM, 10 (2), 165-176. doi:10.5455/AAM.91471


Turabian Style

Makwana, Sarika M, Dipali N Parekh, Prashant Bedarkar, and Pro B J Patgiri. 2021. Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.. Annals of Ayurvedic Medicine, 10 (2), 165-176. doi:10.5455/AAM.91471


Chicago Style

Makwana, Sarika M, Dipali N Parekh, Prashant Bedarkar, and Pro B J Patgiri. "Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.." Annals of Ayurvedic Medicine 10 (2021), 165-176. doi:10.5455/AAM.91471


MLA (The Modern Language Association) Style

Makwana, Sarika M, Dipali N Parekh, Prashant Bedarkar, and Pro B J Patgiri. "Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.." Annals of Ayurvedic Medicine 10.2 (2021), 165-176. Print. doi:10.5455/AAM.91471


APA (American Psychological Association) Style

Makwana, S. M., Parekh, . D. N., Bedarkar, . P. & Patgiri, . P. B. J. (2021) Systematic review on safety and efficacy of Manahshila (Realgar) and its formulations.. Annals of Ayurvedic Medicine, 10 (2), 165-176. doi:10.5455/AAM.91471


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