Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .

Manisha Balu Walunj; Ankush Haushiram Gunjal; Prashant  Bedarkar; Pradeep Kumar  Prajapati

doi:10.5455/AAM.118637

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AAM. 2026; 15(2): 430-442

doi: 10.5455/AAM.118637

Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .

Manisha Balu Walunj, Ankush Haushiram Gunjal, Prashant Bedarkar, Pradeep Kumar Prajapati.

Abstract
Abstract:
Introduction: Laghu Malini Vasanta Rasa (LMVR) is traditionally indicated in Jeerna Jwara and has shown potential in managing Madhumeha (Type 2 Diabetes Mellitus). Mardana Samskara, akin to Bhavana (trituration), is believed to enhance therapeutic efficacy. Aim: To assess whether Mardana Samskara improves LMVR's efficacy in Madhumeha. Methods: Two LMVR samples, identical in composition but differing in Mardana Samskara, were administered (250 mg, twice daily) for eight weeks to 116 randomized patients. Efficacy was evaluated based on symptomatic relief and changes in fasting blood sugar (FBS) and postprandial blood sugar (PPBS) levels. Results: Both formulations improved glycemic control and symptoms (p<0.05). On comparison difference in efficacy between groups was insignificant (p>0.05). However LMVR with Mardana Samskara showed superior efficacy, particularly in subjective parameters (Principle component analysis and coefficient of variation test ). Conclusion: Mardana Samskara enhances LMVR’s therapeutic potential, providing better symptomatic relief and glycemic control in Madhumeha.

Key words: Laghu Malini Vasanta Rasa, Mardana Samskara, Madhumeha, Type 2 Diabetes Mellitus, glycemic control

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Pubmed Style

Walunj MB, Gunjal AH, Bedarkar P, Prajapati PK. Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .. AAM. 2026; 15(2): 430-442. doi:10.5455/AAM.118637

Web Style

Walunj MB, Gunjal AH, Bedarkar P, Prajapati PK. Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .. https://www.aamjournal.in/?mno=118637 [Access: April 16, 2026]. doi:10.5455/AAM.118637

AMA (American Medical Association) Style

Walunj MB, Gunjal AH, Bedarkar P, Prajapati PK. Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .. AAM. 2026; 15(2): 430-442. doi:10.5455/AAM.118637

Vancouver/ICMJE Style

Walunj MB, Gunjal AH, Bedarkar P, Prajapati PK. Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .. AAM. (2026), [cited April 16, 2026]; 15(2): 430-442. doi:10.5455/AAM.118637

Harvard Style

Walunj, M. B., Gunjal, . A. H., Bedarkar, . P. & Prajapati, . P. K. (2026) Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .. AAM, 15 (2), 430-442. doi:10.5455/AAM.118637

Turabian Style

Walunj, Manisha Balu, Ankush Haushiram Gunjal, Prashant Bedarkar, and Pradeep Kumar Prajapati. 2026. Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .. Annals of Ayurvedic Medicine, 15 (2), 430-442. doi:10.5455/AAM.118637

Chicago Style

Walunj, Manisha Balu, Ankush Haushiram Gunjal, Prashant Bedarkar, and Pradeep Kumar Prajapati. "Comparative Efficacy of Two Samples of Laghu Malini Vasanta Rasa with different Mardana (trituration) Samskara in the Management of Madhumeha (Type 2 Diabetes Mellitus): A Randomized Double-Blind Trial .." Annals of Ayurvedic Medicine 15 (2026), 430-442. doi:10.5455/AAM.118637

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