Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati  - A  Herbo-mineral formulation

Bhagyalakshmi B R; Keshava D V; Shobha G Hiremath; Pradeep K Prajapati

2026, Vol: 15, Issue: 3

15 / 3Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Original Research

AAM. 2015; 4(1-2): 18-23

Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation

Bhagyalakshmi B R, Keshava D V, Shobha G Hiremath, Pradeep K Prajapati.

Abstract
Background:Rajahpravartini vati (RPV) is a classical Herbo-mineral formulation indicated for Ammenorrhoea and Dysmenorrhoea.
Objectives: To evaluate Rajahpravartini vati for oestrogenic activity using rat models of uterotrophic bio-assay.
Materials and Method: Immature female rats were randomly divided into five groups as control, standard and three different dose levels of RPV (1/2TED[therapeutic Eqvivalent Dose], TED, 2TED). All these groups were administered with respective medicines for seven consecutive days. Body weight, vaginal opening were noted everyday during the treatment. On the 8th day rats were sacrificed and uterus was collected. Wet and Dry uterine weights were taken. The obtained results were expressed as Mean ±SEM and unpaired t test was applied to compare the effect of test drug with control and standard groups.
Results: Results showed significant oestrogenic activity of RPV at all dose levels, however lower doses (1/2TED) showed highly significant oestrogenic activity in all parameters. Histo-pathologically the trail drug at low doses showed increased endometrial thickness when compared with control group suggesting oestrogenic activity.
Conclusion: Thus the trial drug RPV showed significant oestrogenic activity in all three dose levels better at low doses.

Key words: Oestrogenic activity, Rajahpravartini vati, uterine weight, Uterotrophic bioassay.

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Bhagyalakshmi B R Articles by Keshava D V Articles by Shobha G Hiremath Articles by Pradeep K Prajapati
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

R BB, V KD, Hiremath SG, Prajapati PK. Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation. AAM. 2015; 4(1-2): 18-23.

Web Style

R BB, V KD, Hiremath SG, Prajapati PK. Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation. https://www.aamjournal.in/?mno=187746 [Access: June 26, 2026].

AMA (American Medical Association) Style

R BB, V KD, Hiremath SG, Prajapati PK. Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation. AAM. 2015; 4(1-2): 18-23.

Vancouver/ICMJE Style

R BB, V KD, Hiremath SG, Prajapati PK. Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation. AAM. (2015), [cited June 26, 2026]; 4(1-2): 18-23.

Harvard Style

R, B. B., V, . K. D., Hiremath, . S. G. & Prajapati, . P. K. (2015) Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation. AAM, 4 (1-2), 18-23.

Turabian Style

R, Bhagyalakshmi B, Keshava D V, Shobha G Hiremath, and Pradeep K Prajapati. 2015. Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation. Annals of Ayurvedic Medicine, 4 (1-2), 18-23.

Chicago Style

R, Bhagyalakshmi B, Keshava D V, Shobha G Hiremath, and Pradeep K Prajapati. "Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation." Annals of Ayurvedic Medicine 4 (2015), 18-23.

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

R, B. B., V, . K. D., Hiremath, . S. G. & Prajapati, . P. K. (2015) Experimental Evaluation of Oestrogenic activity of Rajahpravartini vati - A Herbo-mineral formulation. Annals of Ayurvedic Medicine, 4 (1-2), 18-23.


About Annals of Ayurvedic Medicine Annals of Ayurvedic Medicine (AAM) is the organ of ‘Association of Ayurvedic Physicians of India\'(AAPI), which is a national representative body of Ayu ... Read more. For best results, please use Internet Explorer or Google Chrome.	Contact Information Publisher: Association of Ayurvedic Physicians of India Publisher website:https://sapi.org.in/ Editorial Office : Prof Sanjeev Rastogi Vatsala Hospital, Tulsi Das Marg, Lucknow-226003, INDIA Main Office : 6, Ganga Bag Colony, Lanka, Varanasi -221005, INDIA Editorial Contact: Email: info@sapi.org.in Email: rastogisanjeev@rediffmail.com Mobile: 0091-9415022955

About Annals of Ayurvedic Medicine

Contact Information

How to cite this article