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Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study

Nilima Narayanrao Wadnerwar, Shriramji G. Jyotishi, Dhiraj Singh Rajput, Ulhas D. Duragkar.

Abstract
Though the poisons are harmful and dangerous to life, Ayurveda has mentioned their uses therapeutically as medicine after shodhana. This particular process affects the morphological as well as active part of the crude drug. These processes are being used since a very long time. Hence it becomes necessary to study these changes systematically and scientifically with the help of modern methods, so as to give a scientific base to these processes. Abrin, the toxic principle of Gunja (Abrus precatorius Linn), exerts its toxic action by attaching itself to the cell membrane. Its toxic effect is due to its direct action on the parenchymal cells and RBCs. The unpurified Gunja beeja extract if administered into the vein, it causes agglutination of blood. Hence in the present study, shodhana of both red and white variety of Gunja beeja was done in different media (Godugdhha, Kanji and distilled water) by swedana in Dolayanytra. Agglutination process was studied before and after shodhana of Gunja beeja by mixing a drop of Gunja beeja extract into a drop of blood sample of healthy individual of different blood groups on a glass slide. Agglutination was observed in ashodhit samples of both type where as it was absent in all shodhit samples. This explains that after shodhana, the toxic principle has been destroyed

Key words: Shodhana, Abrus precatorius, Agglutination.


 
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How to Cite this Article
Pubmed Style

Wadnerwar NN, Jyotishi SG, Rajput DS, Duragkar UD. Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study. AAM. 2017; 6(1-2): 31-39.


Web Style

Wadnerwar NN, Jyotishi SG, Rajput DS, Duragkar UD. Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study. http://www.aamjournal.in/?mno=263318 [Access: December 16, 2017].


AMA (American Medical Association) Style

Wadnerwar NN, Jyotishi SG, Rajput DS, Duragkar UD. Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study. AAM. 2017; 6(1-2): 31-39.



Vancouver/ICMJE Style

Wadnerwar NN, Jyotishi SG, Rajput DS, Duragkar UD. Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study. AAM. (2017), [cited December 16, 2017]; 6(1-2): 31-39.



Harvard Style

Wadnerwar, N. N., Jyotishi, S. G., Rajput, D. S. & Duragkar, U. D. (2017) Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study. AAM, 6 (1-2), 31-39.



Turabian Style

Wadnerwar, Nilima Narayanrao, Shriramji G. Jyotishi, Dhiraj Singh Rajput, and Ulhas D. Duragkar. 2017. Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study. Annals of Ayurvedic Medicine, 6 (1-2), 31-39.



Chicago Style

Wadnerwar, Nilima Narayanrao, Shriramji G. Jyotishi, Dhiraj Singh Rajput, and Ulhas D. Duragkar. "Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study." Annals of Ayurvedic Medicine 6 (2017), 31-39.



MLA (The Modern Language Association) Style

Wadnerwar, Nilima Narayanrao, Shriramji G. Jyotishi, Dhiraj Singh Rajput, and Ulhas D. Duragkar. "Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study." Annals of Ayurvedic Medicine 6.1-2 (2017), 31-39. Print.



APA (American Psychological Association) Style

Wadnerwar, N. N., Jyotishi, S. G., Rajput, D. S. & Duragkar, U. D. (2017) Effect of shodhana on toxic principle of Gunja Beeja with reference to Agglutination-An in vitro study. Annals of Ayurvedic Medicine, 6 (1-2), 31-39.



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The articles in Annals of Ayurvedic Medicine are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.